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Search Results for " ido1 in 2 "

9

Compounds

Cat No. Product Name Synonyms Targets
T20513 IDO1-IN-1 IDO1 inhibitor 1,2 HzBTZ,IDO1IN1,2-HzBTZ,IDO1-inhibitor-1 IDO
IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.
T11624 IDO1-IN-2 IDO
IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse), and 28 nM (rat), respectively. It has anti-cancer activity.
T60499 IDO1/TDO-IN-2
IDO1/TDO-IN-2 (Compound 1) is a potent IDO1/TDO dual inhibitor with IC50s of 0.1 and 0.07 μM, respectively. IDO1/TDO-IN-2 has the potential for cancer research[1].
T63222 IDO1/2-IN-1
IDO1/2-IN-1 is the first potent, orally active dual IDO1/IDO2 inhibitor, exhibiting antitumor effects with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively.
T63651 IDO1/2-IN-1 hydrochloride
IDO1/2-IN-1 hydrochloride is the first potent dual inhibitor of IDO1 (IC50: 28 nM) and IDO2 (IC50: 144 nM) that is orally active.IDO1/2-IN-1 hydrochloride exhibits antitumor effects.
T1806 IDO-IN-7 NLG919,Navoximod,NLG-919 analogue,GDC-0919 Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
T3S1967 (S)-Indoximod N-ME-Tryptophan,Abrine,L-Abrine Others , Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...
T61385 IDO1/TDO-IN-1
IDO1/TDO-IN-1 (30) is a highly effective inhibitor that targets both IDO1 and TDO enzymes with uncompetitive (Ki = 0.23 μM) and competitive (Ki = 0.73 μM) mechanisms, respectively. This compound, IDO1/TDO-IN-1 (30), exhi...
T37329 PROTAC IDO1 Degrader-1 PROTAC IDO1 Degrader-1
PROTAC IDO1 Degrader-1, a pioneering compound, efficiently targets indoleamine 2,3-dioxygenase 1 (IDO1) for ubiquitination and degradation by recruiting IDO1 to the CRBN E3 ligase, thereby facilitating its entry into the...
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